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Using the IPEA DATA the five macro socioeconomic variables
2018-10-30
Using the IPEA/DATA, the five macro-socioeconomic variables were: the homicide and suicide rate per 100,000 inhabitants, the percentage of poor people, the Gini index as an income inequality measurement, the open unemployment rate and government expenses. These macro-variables were disaggregated for
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The essential autophagy gene beclin BECN is a
2018-10-30
The essential autophagy gene beclin 1 (BECN1) is a haploinsufficient tumor suppressor (Liang et al., 1999; Qu et al., 2003; Yue et al., 2003) that is also located on the breast cancer tumor susceptibility chromosomal locus 17q21, ~150kb centromeric to BRCA1 (Aita et al., 1999). Monoallelic loss of B
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Interrogating the underlying pathophysiology prior to
2018-10-30
Interrogating the underlying pathophysiology prior to the full-blown manifestations can help clarify some confounding effects. For example, extant neuroimaging research on established BP has suggested that the volume of gray matter (GM) decreases in the regions underpinning emotion processing and re
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We have presented data showing the
2018-10-30
We have presented data showing the discovery proteomic identification of three plasma proteins which are putative predictive marker of survival for SqCC NSCLC patients after radiotherapy. The level of two of these proteins (LRG1 and CRP) has been shown to be predictive with regard to survival, with
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noradrenaline This study has highlighted the complexity of o
2018-10-30
This study has highlighted the complexity of operationally defining compensation in neurodegenerative diseases such as HD. The previous literature in HD has thus far failed to address this issue, instead making assumptions of putative compensation based solely on increased activation or connectivity
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Petrovics et al demonstrated that
2018-10-30
Petrovics et al. demonstrated that the statistical power can be improved by combining and integrating different data types including whole genome sequencing (WGS), FISH assays and SNP array data. Despite the initial discovery was based on only 7 CA and 7 AA tumor/normal pairs of WGS data, the findin
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br Materials and Methods br Results br Discussion The presen
2018-10-30
Materials and Methods Results Discussion The present study demonstrated that both rs6435156C>T and rs1048829G>T variant genotypes in the 3′UTR of BMPR2 were associated with increased risk of COPD in a southern Chinese population. COPD smokers carrying the T variant (CT and TT) of rs6435156
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Givinostat Comparing cognitive and clinical measures across
2018-10-30
Comparing cognitive and clinical measures across all case groups and controls (Table 2) showed group effects for all measures, except physical anhedonia, and WAIS Perceptual Organization, Verbal Comprehension, and Working Memory indexes. Examining symptoms among case groups showed significant effect
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In this study we modeled VC to
2018-10-30
In this study, we modeled VC to project DEP in Europe given changes in climate. Throughout this study, we have included DTR in all of our VC calculations. We expanded our previous relative VC model to VC, by including temperature dependent dynamics in the female vector-to-human population ratio (Li
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The simultaneous analysis of ATI and FC levels shows that
2018-10-29
The simultaneous analysis of ATI and FC levels shows that the therapeutic escalation is associated to high values of either these variables. Importantly, their impact in the need of a future therapeutic escalation is independent of the disease severity, as is shown by the fact that neither histologi
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PND-1186 Neuraminidase inhibitors NAI are the most frequentl
2018-10-29
Neuraminidase inhibitors (NAI) are the most frequently used antiviral drug for management of influenza infection. Early NAI treatment was associated with shorter illness duration, and is most beneficial when treatment started within 2days of illness onset (Lee et al., 2015). However, except for indu
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br Conflict of Interest Statement br
2018-10-29
Conflict of Interest Statement Search Strategy and Selection Criteria Data for this review were identified by searches of PubMed, using the following search terms in various combinations: “NFIB”, “cancer”, “development”, “cellular differentiation”, “NFI transcription factors”. Articles resulti
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The data presented here shows
2018-10-29
The data presented here shows that inhibition of the 26S proteasome causes significant changes in the expression of Card10, Dffb, Traf3 and Trp53bp2 genes. In addition, four genes were found consistently downregulated in response to treatment with bortezomib for 24h. The genes downregulated were Bcl
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Specifications table br Value of data br Experimental
2018-10-29
Specifications table Value of data 1. Experimental design, materials and methods 2. Direct link to deposited data Deposited data can be found here: http://www.ncbi.nlm.nih.gov.eleen.top/GBRH01000000. 3. Nucleotide sequence accession number The assembled and annotated A. donax USA caspa
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br Acknowledgements We are indebted to K Basler S
2018-10-29
Acknowledgements We are indebted to K. Basler, S. Bray, M. Freeman E. Martín-Blanco and F. Schweisguth for fly lines. Some antisera used in this work were obtained from the Developmental Studies Hybridoma Bank (DSHB) developed under the auspices of the NICHD and maintained by the University of Io
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