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The method used in our study
2018-11-09

The method used in our study for measuring epigenetic age was based on a model trained on genome-wide DNA methylation extracted from WBC (Hannum et al., 2013). As our measurements were taken from extracted WBC, epigenetic age measured in our study could be a proxy measure for the immune response to
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To evaluate the capacity of the newly
2018-11-09

To evaluate the capacity of the newly isolated recombinants to express BHV-1 UL49.5, total protein was isolated from virus-infected cells and analyzed by immunoblotting. BHV UL49.5 protein only accumulated in BV49.5-infected cells and was not detected in cells infected with the BV49.5-FS variant, wi
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A secondary outcome of interest was the
2018-11-09

A secondary outcome of interest was the arrest to birth interval. Out of 34 babies for whom the information is known, 4 newborns (11.8%) were delivered within 5min or less, 12 (35.3%) delivered from 5 to 11min, 8 (23.5%) delivered from 11 to 21min, and 10 (29.4%) delivered more than 21min after the
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Sulindac sulfide Br gnard et al also
2018-11-09

Brégnard et al. also discovered that some of the cytoplasmic DNA resulted from enhanced LINE-1 retrotransposition, a phenomenon others have associated with inflammatory diseases (). That inhibitors of reverse transcription diminished cytokine production in the FA Sulindac sulfide is compatible with
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The second part of this
2018-11-09

The second part of this study evaluated the detection of NTM in clinical specimens by PCR in comparison to culture (Fig. 2). Here we used the Roche COBAS™ MTB assay supplemented with an additional pan Mycobacterium genus probe. The Mycobacterium genus probe is highly sensitive but compromised by lim
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Polyubiquitylation leading to proteolytic degradation by
2018-11-09

Polyubiquitylation leading to proteolytic degradation by the 26S proteasome is involved in all aspects of cell physiology. The highly coordinated process ensures the selective and timely turnover of proteins, thereby controlling cellular activity and maintaining cell and tissue homeostasis (Glickman
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Assuming that quantification of total Tregs using demethylat
2018-11-09

Assuming that quantification of total Tregs using demethylation of the FOXP3 gene or flow cytometry are correlates of true Tregs, these studies suggest that circulating Tregs may not be a strong predictor of myocardial infarction that could translate into a usable predictor in the clinic. The studie
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According to HCV status we found a stronger association betw
2018-11-09

According to HCV status, we found a stronger association between low TGF-β1 concentrations and the risk of death from HCC among the HCV-positive group compared to the HCV-negative group, suggesting that the predictive value of TGF-β1 is more potent in higher risk HCV-positive individuals. This findi
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br Methods br Results br Discussion The
2018-11-09

Methods Results Discussion The intriguing relationship between commensal microbes and atherosclerosis has received increasing attention over the past few years. However, the specific mechanisms whereby commensal microbes regulate the development of atherosclerosis are just beginning to be e
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Other investigators have reported default mode network chang
2018-11-09

Other investigators have reported default mode network changes in infancy (Damaraju et al., 2013; Gao et al., 2009, 2013), and we note 29 involved default mode ROIs in our 100% consensus feature set (23 would be expected by chance, alone, based on 50 default mode ROIs of the 230 used at input, and 1
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The main aim of the present functional magnetic resonance
2018-11-09

The main aim of the present functional magnetic resonance mps1 (fMR-A) study with children was to further constrain our understanding of age-related changes in the neural correlates of symbolic numerical magnitude representation. The fMR-A design (adapted from adult studies by Holloway et al. (2012
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Laboratory studies have shown that total sleep deprivation f
2018-11-09

Laboratory studies have shown that total sleep deprivation for 24–72h impairs the performance of many tasks [1,6,7]. So, it is possible that the lack of sleep may affect a basic cognitive process, such as attention, working memory or executive functions, crucial for the execution of a broad range of
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Introduction The human circulatory system consists
2018-11-09

Introduction The human scopolamine hydrobromide consists of the heart and the blood vessels, which together maintain a continuous blood flow throughout the body. The heart is a hollow muscle that can pump blood throughout the body, in normal state it beats about 60–80 times per minute, but during
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br Introduction Dissociated animal neurons are able
2018-11-09

Introduction Dissociated animal neurons are able to form a neuronal network within a couple of days after being plated on a microelectrode array (MEA) with adequate density [6,10,11]. The developing neuronal network spikes spontaneously. An MEA can trace this spontaneous spiking activity (SSA), w
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br En el verano del a o el
2018-11-09

En el verano del año 2010 el Consejo General del Banco Central Europeo decidió que el conjunto de 27 bancos centrales de la Unión Europea participaran conjuntamente en una investigación formulando nuevos conceptos, modelos y medidas de regulación y supervisión macroprudencial. El grupo de investig
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