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A limited number of studies have been
2018-11-05

A limited number of studies have been conducted on the simultaneous oxidation of different Cy3-dUTP of organochloride compounds and their relative performance with regards to photocatalyst adsorption selectivity. In this study, three structurally dissimilar organochloride compounds will be analysed
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The fluoroquinolone group gemifloxacin is one
2018-11-05

The fluoroquinolone group (gemifloxacin) is one of the most important pharmaceuticals used universal wide for humans and veterinary purposes. The occurrence of broad-spectrum antibiotics similar to these in aquatic environments may approach serious threats to the ecosystem and human health by making
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In three cases of tumor of
2018-11-05

In three cases of tumor of unknown origin it was not possible to make a specific genetic diagnosis as all cfDNA had an identical genotype to the patient. It is possible that ctDNA was present and that the tumors were non-gestational but as the ctDNA showed no instability at the loci analyzed the ctD
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Categorization of AD in the epidemiological simulations diff
2018-11-05

Categorization of AD in the epidemiological simulations differs from some previous studies for China and the US (Wang et al., 2008; AA, 2015) which employed a three-state (mild, moderate, severe) categorization. The current two-state specification of AD (stage 1 and stage 2) encapsulates mild and mo
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br Materials and methods br Funding source
2018-11-05

Materials and methods Funding source Results Discussion In this study, we report a global evaluation of the state of activation of the immune, endothelial and coagulation systems in 120 treated patients aviremic for at least 2years. A first conclusion is that these patients overall pres
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Our previous study demonstrated that HDAC
2018-11-05

Our previous study demonstrated that HDAC inhibition contributed to the anticancer effect of statins (Lin et al., 2008). Combining anti-cancer drugs with different mechanisms is a rational approach to improve efficacy. JMF3086, synthesized to inhibit both HDACs and HMGR, exhibits significant benefit
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Finally in the context of this adipose specific
2018-11-05

Finally, in the context of this adipose specific FABP4 transgenic (over expression) mouse model phenotype, it is essential to discuss the caveats of this animal model. In the last five years several reviews have highlighted the advantages and disadvantages of the different promoters (for example FAB
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The ongoing efforts to identify targeted therapy for
2018-11-05

The ongoing efforts to identify targeted therapy for dedifferentiated, metastatic PTC has led to empirically driven clinical trials of different tyrosine kinase receptor inhibitors that disrupt MEK, VEGFR, FGFR and other signaling pathways. These therapies were intended to slow disease progression,
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br Materials and methods br Results
2018-11-05

Materials and methods Results and discussion Conclusion An RSM based on CCRD and a multi-layer neural network (4-5-1 ANN architecture) models were developed in order to justify the aim of the current research. The input variables were temperature, time, volume of solvent, and particle size,
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The etiology was considered idiopathic in all cases
2018-11-05

The etiology was considered idiopathic in all cases, based on the high number of complementary exams performed. In the 6 cases in whom the anti-streptolysin-O levels was obtained, only one demonstrated a mildly high level, which does not support the hypothesis of streptococcal infection as a main tr
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A detailed analysis of hypocretinergic neuronal activity
2018-11-05

A detailed analysis of hypocretinergic neuronal activity shows that these neurons are strongly activated when animals are exploring an unknown environment (exploratory motor activity) [50]. In fact, in this study, the number of Hcrt+Fos+neurons was approximately 10 times greater during exploratory m
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While obesity maintained an intense association in the bivar
2018-11-05

While obesity maintained an intense association in the bivariate analysis (OR: 9.29), this association was lost in the multivariate analysis, where it was adjusted by neck circumference, which maintained a significant association. This is consistent with the results obtained by Preis et al. [26] in
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Our results are in accordance with
2018-11-03

Our results are in accordance with recent studies using RT combined with mAb-mediated blockade of PD-1 or PD-L1 in mouse models of melanoma (Sharabi et al., 2015), breast carcinoma (Deng et al., 2014; Sharabi et al., 2015), colon adenocarcinoma (Deng et al., 2014), glioma (Zeng et al., 2013) and mul
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We have also observed that elevated Glut on monocytes is
2018-11-03

We have also observed that elevated Glut1 on monocytes is associated with high sCD163 plasma levels within this HIV+ population, supporting a model by which chronic HIV infection drives metabolic activation of monocytes in response to inflammatory changes. This results from metabolic reprogramming w
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br Acknowledgments This work has been supported by the
2018-11-03

Acknowledgments This work has been supported by the California Institute for Telecommunications and Information Technology (CALIT2) under Grant number 2014CSRO 136. Experimental design, materials and methods Acknowledgments This work has been supported by the California Institute for Telec
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